Preferred Label : Monoclonal Antibody B6.2F(ab')2;
NCIt synonyms : MOAB B6.2F(AB')2; Monoclonal Antibody B6 2F ab 2;
NCIt definition : A divalent F(ab)2 fragment of the monoclonal antibody (MoAb) B6.2 directed against
the tumor-associated glycoprotein (TAG-90) found on the surface of primary and metastatic
human mammary tumors.. MoAb B6.2 F(ab)2 fragments are obtained through pepsin digestion.
The advantage of using MoAb B6.2 F(ab)2 fragments over whole antibodies is that they
have reduced immunogenicity, better penetration of tissues, rapid clearance from the
body and that they do not induce precipitation.;
Origin ID : C29209;
UMLS CUI : C1513433;
Semantic type(s)
- chemical_or_drug_has_mechanism_of_action
