Preferred Label : Monoclonal Antibody 8.2 F(ab);
NCIt synonyms : MOAB 8.2 FAB; Monoclonal Antibody 8 2 F ab;
NCIt definition : A monovalent Fab fragment of the mouse monoclonal antibody (MoAb) 8.2 raised against
human melanoma-associated cell surface marker p97. MoAb 8.2 Fab fragments are obtained
through papain digestion in the presence of cysteine. The advantage of using 8.2 Fab
fragments over whole antibodies is that they have reduced immunogenicity, better penetration
of tissues, rapid clearance from the body and that they do not induce precipitation.;
Origin ID : C29203;
UMLS CUI : C1513426;
Semantic type(s)
- chemical_or_drug_has_mechanism_of_action
