Preferred Label : Monoclonal Antibody 48.7 F(ab);
NCIt synonyms : MOAB 48.7 FAB; Monoclonal Antibody 48 7 F ab;
NCIt definition : A Fab fragment of the mouse monoclonal antibody (MoAb) 48.7. MoAb 48.7 Fab (fragment
antigen binding) recognizes proteoglycan antigen expressed on the cell surface of
melanoma cells. The Fab fragments are obtained through papain digestion in the presence
of cysteine. The advantage of using MoAb 48.7 Fab fragments over whole antibodies
is that they have reduced immunogenicity, better penetration of tissues, rapid clearance
from the body and that they do not induce precipitation.;
Origin ID : C29200;
UMLS CUI : C1513420;
Semantic type(s)
- chemical_or_drug_has_mechanism_of_action
