Preferred Label : Mitindomide;
NCIt synonyms : 4, 8-Ethenopyrrolo[3',4':3,4]cyclobut[1,2-f]isoindole-1,3,5,7(2H, 6H)tetrone, octahydro-;
NCIt definition : A bisdioxopiperazines analog with antineoplastic activity. Mitinomide inhibits topoisomerase
II and slowly promotes DNA-interstrand cross-linking, thereby inhibiting DNA repair,
RNA and protein synthesis. This agent acts without increasing topoisomerase II-DNA
covalent cleavable complex formation, as do most topoisomerase inhibitors. (NCI04);
UNII : DK61ZER6T7;
InChIKey : DRCJGCOYHLTVNR-ZUIZSQJWSA-N;
CAS number : 10403-51-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 10403-51-7
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G-SRS /a ;
Chemical formula : C14H12N2O4;
NSC code : 284356;
Origin ID : C29195;
UMLS CUI : C0066593;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
