Preferred Label : Michellamine B;
NCIt synonyms : 6,8-Isoquinolinediol, 5,5'-(1,1'-dihydroxy-8,8'-dimethoxy-6,6'-dimethyl(2,2'-binaphthalene)-4,4'-diyl)bis(1,2,3,4-tetrahydro-1,3-dimethyl)-,
(1R,1'R,3R,3'R,5R,5'S)-;
NCIt definition : A natural plant alkyloid with activity against human immunodeficiency viruses (HIV)
1 and 2. Michellamine B inhibits HIV reverse transcriptase (RT) activity and HIV-induced
cellular fusion and syncytium formation, thereby inhibiting viral propagation. Michellamine
B also inhibits human DNA polymerases alpha and beta.;
CAS number : 137893-48-2;
Chemical formula : C46H48N2O8;
NSC code : 649324;
Origin ID : C29193;
UMLS CUI : C0128431;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
