Preferred Label : KNI-272;
NCIt synonyms : 4-Thiazolidinecarboxamide, N-(1,1-dimethylethyl)-3- [2-hydroxy-3-[[2-[[(5-isoquinolinyloxy)acetyl]amino]-3-
(methylthio)-1-oxopropyl]amino]-1-oxo-4-phenylbutyl]-,[4R-[3[2S*, 3S*(R*)],4R*]];
NCIt definition : A synthetic peptide-based antiviral agent. As a peptidomimetic substrate containing
an unnatural amino acid, allophenylnorstatine, KNI-272 selectively binds to and inhibits
the human immunodeficiency virus (HIV) 1 and 2 proteases, thereby preventing cleavage
of the gag-pol viral polyprotein and resulting in the release of immature, noninfectious
virions. (NCI04);
UNII : MUL0OE3YBF;
CAS number : 147318-81-8;
NSC code : 651714;
Origin ID : C29140;
UMLS CUI : C4520815;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- concept_is_in_subset
