Insulin Lispro

Preferred Label : Insulin Lispro;

NCIt synonyms : Lispo Insulin;

NCIt definition : A recombinant therapeutic agent which is chemically identical to or similar to endogenous human insulin. In lispro insulin, the amino acid proline at B-28 and the amino acid lysine at B-29 are reversed, resulting in the rapid dissolution of this insulin to a monomer that is absorbed rapidly after subcutaneous administration. Lispro insulin is equipotent to human insulin on a molar basis but its effects are faster and of shorter duration. Endogenous insulin, a pancreatic hormone composed of two polypeptide chains, is important in the normal metabolism of carbohydrates, proteins and fats, promoting glucose utilization and protein synthesis; it has anabolic effects on many types of tissues. (NCI04);

UNII : GFX7QIS1II;

CAS number : 133107-64-9;

Drug name : Humalog;

Chemical formula : C257H383N65O77S6;

Details

Origin ID

C29123;

UMLS CUI

C0293359;

Automatic exact mappings (from CISMeF team)
- Human insulin analog product (product) [Inactive SNOMED CT concept]
See also inter- (CISMeF)
- Product containing insulin lispro (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Hormone [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Insulin lispro (substance) [SNOMED CT concept]
- Product containing insulin lispro (medicinal product) [SNOMED CT concept]
- insulin lispro [ATC Code]
- insulin lispro [MeSH concept]
- insulin lispro [ATC Code]
- insulin lispro [ATC Code]
- insulin lispro [MeSH Descriptor]
- insulin lispro [Substance BNPC]
Validated automatic mappings to BTNT
- insulin lispro [ATC Code]
- insulin lispro [ATC Code]
- insulin lispro [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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