Gatifloxacin - CISMeF

Preferred Label : Gatifloxacin;

NCIt synonyms : 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic acid;

NCIt definition : A synthetic 8-methoxyfluoroquinolone with antibacterial activity against a wide range of gram-negative and gram-positive microorganisms. Gatifloxacin exerts its effect through inhibition of DNA gyrase, an enzyme involved in DNA replication, transcription and repair, and inhibition of topoisomerase IV, an enzyme involved in partitioning of chromosomal DNA during bacterial cell division.;

UNII : L4618BD7KJ;

InChIKey : RMJMZKDEVNTXHE-UHFFFAOYSA-N;

CAS number : 112811-59-3; 180200-66-2;

Drug name : Tequin; Zymar; Gatiflo;

Molecule name : AM-1155; BMS-206584-01;

Chemical formula : 2C19H22FN3O4.3H2O;

ChEBI ID : CHEBI:5280;

Details

Origin ID

C29070;

UMLS CUI

C0753645;

False automatic mappings
- Product containing gatifloxacin (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Gatifloxacin [MeSH Descriptor]
- Gatifloxacin [LOINC component]
- Gatifloxacin (substance) [SNOMED CT concept]
- Product containing gatifloxacin (medicinal product) [SNOMED CT concept]
- gatifloxacin [ATC Code]
- gatifloxacin [ATC Code]
- gatifloxacin [MeSH concept]
Validated automatic mappings to BTNT
- gatifloxacin [ATC Code]
- gatifloxacin [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Gatifloxacin Mesylate [NCIt concept]
is_free_acid_or_base_form_of
- Gatifloxacin Mesylate [NCIt concept]

Keyword's position in hierarchy(ies) :

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