Dyclonine - CISMeF

Preferred Label : Dyclonine;

NCIt synonyms : 1-Propanone,1-(4-butoxyphenyl)-3-(1-piperidinyl)-;

NCIt definition : An unclassified compound with local anesthetic effect. Dyclonine reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membrane's permeability to sodium ions, leading to an increased threshold for excitation. This reversibly stabilizes the membrane and inhibits depolarization, leading to the failure of a propagated action potential and subsequent conduction blockade. This results in a transient and reversible loss of sensation in a localized area of the body.;

UNII : 078A24Q30O;

InChIKey : BZEWSEKUUPWQDQ-UHFFFAOYSA-N;

CAS number : 586-60-7;

Chemical formula : C18H27NO2;

ChEBI ID : CHEBI:4724;

Details

Origin ID

C29015;

UMLS CUI

C0058831;

Automatic exact mappings (from CISMeF team)
- Dyclonine [ICHI extension code]
Currated CISMeF NLP mapping
- Dyclonine [ICD-11 Extension code]
- Dyclonine (substance) [SNOMED CT concept]
- dyclonine [MeSH concept]
- dyclonine [MeSH Supplementary Concept]
- dyclonine [SNOMED Notion]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Dyclonine [ICD-11 Extension code]
- Dyclonine (substance) [SNOMED CT concept]
- Product containing dyclonine (medicinal product) [SNOMED CT concept]
- dyclonine [ATC Code]
- dyclonine [ATC Code]
- dyclonine [MeSH concept]
- dyclonine [SNOMED Notion]
- dyclonine [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- dyclonine [ATC Code]
- dyclonine [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Dyclonine Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Dyclonine Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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