NCIt definition : The hydrochloride salt form of diphenoxylate, a piperidine derivate, chemically related
to narcotic meperidine, with antidiarrheal activity and devoid of central nervous
system (CNS) activity. Diphenoxylate acts on opioid receptors in the gastrointestinal
tract, thereby decreasing gastrointestinal motility and causing constipation or preventing
diarrhea.;