Preferred Label : Tetrandrine;
NCIt synonyms : Pheanthine; Berbaman, 6, 6',7,12-trtramethoxy-2,2'-dimethyl-, (1beta)-(PM)-(9CI); Sinomenine A; (1beta)-6,6',7,12-tetramethoxy-2,2'-dimethylberbaman; Tetrandrin; (S,S)-Tetrandrine; D-tetrandrine; Tetrandrine, D-;
NCIt related terms : TETRANDRINE, ( )-;
NCIt definition : A natural, bis-benzylisoquinoline alkaloid isolated from the root of the plant Radix
stephania tetrandrae. Tetrandrine non-selectively inhibits calcium channel activity
and induces G1 blockade of the G1 phase of the cell cycle and apoptosis in various
cell types, resulting in immunosuppressive, anti-proliferative and free radical scavenging
effects. This agent also increases glucose utilization by enhancing hepatocyte glycogen
synthesis, resulting in the lowering of plasma glucose. (NCI04);
UNII : 29EX23D5AJ;
InChIKey : WVTKBKWTSCPRNU-KYJUHHDHSA-N;
CAS number : 518-34-3;
Chemical formula : C38H42N2O6;
NSC code : 77037;
Codes from synonyms : 50377;
Origin ID : C28952;
UMLS CUI : C0076316;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
