Cefpodoxime Proxetil

Preferred Label : Cefpodoxime Proxetil;

NCIt synonyms : Cefpodoxime;

NCIt definition : A third generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefpodoxime's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefpodoxime inhibits bacterial septum and cell wall synthesis formation.;

UNII : 2TB00A1Z7N;

InChIKey : LTINZAODLRIQIX-FBXRGJNPSA-N;

CAS number : 87239-81-4;

Drug name : Vantin;

ChEBI ID : CHEBI:3505;

Details

Origin ID

C28916;

UMLS CUI

C0108938;

Automatic exact mappings (from CISMeF team)
- Cefpodoxime [LOINC component]
- Cefpodoxime [ICD-11 Extension code]
- cefpodoxime [MeSH concept]
- cefpodoxime [ATC Code]
- cefpodoxime [SNOMED Notion]
See also inter- (CISMeF)
- Product containing cefpodoxime (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Cefpodoxime Proxetil [MeSH Descriptor]
- Cefpodoxime proxetil (substance) [SNOMED CT concept]
- cefpodoxime proxetil [Substance BNPC]
- cefpodoxime proxetil [SNOMED Notion]
- cefpodoxime proxetil [MeSH concept]
Validated automatic mappings to NTBT
- Cefpodoxime [MeSH Descriptor]
- Cefpodoxime [SMS substance]
- Cefpodoxime (substance) [SNOMED CT concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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