Cefaclor - CISMeF

Preferred Label : Cefaclor;

NCIt synonyms : Cefaclor Hydrate;

NCIt definition : A beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. Cefaclor binds to and inactivates penicillin-binding proteins (PBP) located in bacterial cytoplasmic membranes. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.;

UNII : 69K7K19H4L;

InChIKey : WKJGTOYAEQDNIA-IOOZKYRYSA-N;

CAS number : 70356-03-5;

Chemical formula : C15H14ClN3O4S.H2O;

Details

Origin ID

C28911;

UMLS CUI

C0007537;

Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Cefaclor [ICD-11 Extension code]
- Cefaclor [LOINC component]
- Cefaclor (substance) [SNOMED CT concept]
- Product containing cefaclor (medicinal product) [SNOMED CT concept]
- cefaclor [ATC Code]
- cefaclor [Substance BNPC]
- cefaclor [MeSH concept]
- cefaclor [SNOMED Notion]
- cefaclor [MeSH Descriptor]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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