" /> Calcipotriene - CISMeF





Preferred Label : Calcipotriene;

NCIt synonyms : Calcipotriol;

NCIt definition : A synthetic vitamin D derivative usually formulated for topical dermatological use, antipsoriatic Calcipotriene (calcipotriol) competes equally with active 1,25-hydroxy-2D3 (the natural form of vitamin D) for 1,25-hydroxy-2D3 receptors in regulating cell proliferation and differentiation. It induces differentiation and suppresses proliferation of keratinocytes, reversing abnormal keratinocyte changes in psoriasis, and leads to normalization of epidermal growth. (NCI04);

UNII : 143NQ3779B;

InChIKey : LWQQLNNNIPYSNX-UROSTWAQSA-N;

CAS number : 112828-00-9; 112965-21-6; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 112828-00-9 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 112965-21-6 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Dovonex;

Chemical formula : C27H40O3;

ChEBI ID : CHEBI:50749;

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02/06/2024


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