Clomesone - CISMeF

Preferred Label : Clomesone;

NCIt synonyms : Chlorethyl SOSO; 2-Chloroethyl (methylsulfonyl)methanesulfonate;

NCIt definition : The 2-chloroethyl ester of (methylsulfonyl) methanesulfonic acid with potential antineoplastic effects. Acting as a chloroethylating agent, clomesone induces the formation of DNA interstrand crosslinks in some cell lines, and exhibits antitumor activity in some animal models. Alkylating agents exert cytotoxic and, in some cases, chemotherapeutic effects by transferring alkyl groups to DNA, thereby damaging DNA and interfering with DNA synthesis and cell division. (NCI04);

UNII : 2J031W0YZI;

InChIKey : SEHSPJCWCBQHPF-UHFFFAOYSA-N;

CAS number : 88343-72-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 88343-72-0 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : SRI 6155;

Chemical formula : C4H9ClO5S2;

NSC code : 338947;

Details

Origin ID

C28888;

UMLS CUI

C0055920;

Currated CISMeF NLP mapping
- clomesone [MeSH concept]
- clomesone [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- clomesone [MeSH concept]
- clomesone [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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