Preferred Label : Chimeric Monoclonal Antibody B72.3;
NCIt synonyms : Chimeric B72.3; Chimeric Monoclonal Antibody B72 3;
NCIt definition : A synthetic chimeric molecule in which a mouse monoclonal antibody variable region
directed against the tumor-associated glycoprotein 72 (TAG-72) is fused to a human
antibody constant region. This agent reacts to most human adenocarcinomas (colorectal,
gastric, pancreatic, ovarian, endometrial, mammary) but has weak or undetectable reactivity
to most normal tissues. (NCI04);
Origin ID : C28886;
UMLS CUI : C1516479;
Semantic type(s)
- chemical_or_drug_has_mechanism_of_action
