Preferred Label : Aphidicoline Glycinate;
NCIt definition : A tetracyclic diterpene antibiotic isolated from the fungus Cephalosporium aphidicola
and other fungal species with potential antineoplastic activity. Aphidicoline glycinate
blocks the cell cycle at early S-phase by specifically inhibiting DNA polymerases
in eukaryotic cells, induces apoptosis, and stops the growth of eukaryotic cells and
certain viruses by selectively inhibiting DNA polymerase II or viral-induced DNA polymerases.
(NCI04);
Origin ID : C28802;
UMLS CUI : C1516035;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- concept_is_in_subset
