9-Ethyl 6-Mercaptopurine

Preferred Label : 9-Ethyl 6-Mercaptopurine;

NCIt synonyms : 9-Ethyl 6-MP; 9-Ethyl 6-Mercaptopurine;

NCIt definition : A synthetic alkyl derivative prodrug of the antineoplastic agent 6-mercaptopurine (6-MP). In vivo, 9-ethyl 6-mercaptopurine appears to be converted to 6-MP, which substitutes for the normal nucleoside and fraudulently incorporates into DNA and inhibits de novo purine synthesis, thereby inducing cell death. (NCI04);

CAS number : 5427-20-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 5427-20-3 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

NSC code : 14575;

Details

Origin ID

C28789;

UMLS CUI

C0626019;

Currated CISMeF NLP mapping
- 9-ethyl-6-mercaptopurine [MeSH concept]
- 9-ethyl-6-mercaptopurine [MeSH Supplementary Concept]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- 9-ethyl-6-mercaptopurine [MeSH concept]
- 9-ethyl-6-mercaptopurine [MeSH Supplementary Concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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