Preferred Label : Alveoli Epithelial Hyperplasia of the Mouse Pulmonary System;
Alternative definition : MMHCC: Solitary or multiple foci of increased cellularity distal to terminal bronchioles.
The background of broncho-alveolar architecture remains detectable, and epithelial
cells are usually single layered. Round to oval hypertrophic type II pneumocytes with
abundant eosinophilic cytoplasm line alveolar walls. In bronchiolar subvariant, also
called bronchiolization of alveoli, alveolar walls are lined by cuboidal to columnar
cells with features of bronchiloar differentiation such as formation of cilia, Clara
cell resemblance and presence of mucous granules. Foci of consolidation may indicate
early stages of adenoma formation. Macrophages may be present in the alveolar lumens.;
Origin ID : C28623;
UMLS CUI : C1515932;
Semantic type(s)
- eo_disease_has_associated_eo_anatomy
