Preferred Label : Side Effect;
NCIt definition : The term was used in various ways in the past, to describe unintended effects of medical
intervention, usually negative (unfavourable), but also positive (favourable) ones.
It is recommended that this term no longer be used and particularly should not be
regarded as synonymous with adverse event or adverse reaction.;
Alternative definition : CDISC-GLOSS: Any action or effect of a drug or treatment other than the intended effect.
Negative or adverse effects may include headache, nausea, hair loss, skin irritation,
or other physical problems. Experimental drugs must be evaluated for both immediate
and long-term side effects. [After Spilker, B. Guide to Clinical Trials. Lippincott
Williams & Wilkins. 2000. Page xxiv; Finding and Learning about Side Effects (adverse
reactions), July 2018; What are side effects?, August 2018] See also adverse reaction,
treatment effect, therapeutic effect.; NCI-GLOSS: A problem that occurs when treatment affects healthy tissues or organs.
Some common side effects of cancer treatment are fatigue, pain, nausea, vomiting,
decreased blood cell counts, hair loss, and mouth sores.; MRCT-Ctr: A health change that is not the intended effect of the treatment and usually
considered a problem. (https://mrctcenter.org/glossaryterm/side-effect/);
Codes from synonyms : CDR0000046580;
Origin ID : C2861;
UMLS CUI : C0879626;
Automatic exact mappings (from CISMeF team)
Currated CISMeF NLP mapping
Semantic type(s)
UMLS correspondences (same concept)
concept_is_in_subset