Preferred Label : Recombinant Adenovirus-hIFN-beta;
NCIt synonyms : Ad-hIFN-beta;
NCIt related terms : BG00001;
NCIt definition : A recombinant replication-defective adenovirus which encodes the gene for the cytokine
human interferon-beta (IFN-beta). Once inserted into and replicating in host tumor
cells, recombinant adenovirus-hIFN-beta expresses human IFN-beta, which may stimulate
an antiproliferative natural killer (NK) cell response against tumor cells and induce
caspase-mediated tumor cell apoptosis. (NCI04);
Alternative definition : NCI-GLOSS: A gene therapy agent that is being studied in the treatment of cancer.
It belongs to the family of drugs called biological response modifiers.;
Molecule name : BG00001;
Codes from synonyms : CDR0000340925;
Origin ID : C28550;
UMLS CUI : C1527241;
Semantic type(s)
- concept_is_in_subset
