Preferred Label : J5 Antiserum;
NCIt synonyms : Antiserum to Endotoxin Core;
NCIt definition : An antiserum raised against endotoxins of Escherichia coli J5 strain with potential
antibacterial activity. J5 antiserum reacts with lipid A, the key endotoxic component
of the lipopolysaccharides (LPS), found mostly in gram-negative bacteria. By binding
to endotoxins, J5 antiserum prevents the initiation of a cascade of events in host
cells, including the production of pro-inflammatory cytokines that eventually leads
to the sepsis syndrome.;
Origin ID : C28548;
UMLS CUI : C1134511;
Semantic type(s)
- concept_is_in_subset
