Bismuth Bi213 Monoclonal Antibody M195

Preferred Label : Bismuth Bi213 Monoclonal Antibody M195;

NCIt definition : A radioimmunoconjugate consisting of murine monoclonal antibody (M195) and bismuth 213 (Bi213). Monoclonal antibody M195 binds to CD33, a surface antigen expressed by myelogenous leukemia cells. Bismuth 213 is an isotope that emits short-ranged high-energy alpha particles. This radioimmunoconjugate selectively delivers alpha particle-mediated cytotoxicity to leukemic cells, thereby limiting the exposure of normal tissues to ionizing radiation. (NCI04);

Details

Origin ID

C28502;

UMLS CUI

C0935824;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
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- NCI Drug Dictionary Terminology [NCIt concept]
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- Bismuth Bi213 Monoclonal Antibody M195/Cytarabine/Filgrastim [NCIt concept]

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