Actinomycin F1

Preferred Label : Actinomycin F1;

NCIt synonyms : Actinomycin KS4;

NCIt definition : A chromopeptide antineoplastic antibiotic isolated from the bacterium Streptomyces chrysomallus. Actinomycin F1 intercalates into the minor groove of DNA and binds to topoisomerase II, leading to the inhibition of DNA replication and RNA and protein synthesis. (NCI04);

UNII : D8HJS52NSZ;

CAS number : 1402-44-4;

Molecule name : KS4;

Details

Origin ID

C2844;

UMLS CUI

C1515876;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Antibiotic [UMLS semantic type]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

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