NCIt related terms : SELENOMETHIONINE; Seleno-l-methionine;
NCIt definition : The amino acid methionine with selenium substituting for the sulphur moiety. Methionine
is an essential amino acid in humans, whereas selenium is a free-radical scavenging
anti-oxidant, essential for the protection of various tissues from the damages of
lipid peroxidation. As a trace mineral that is toxic in high doses, selenium is a
cofactor for glutathione peroxidase, an anti-oxidant enzyme that neutralizes hydrogen
peroxide. L-Selenomethionine is considered a safe, efficacious form of selenium and
is readily bioavailable. Selenium may be chemoprotective for certain cancers, particularly
prostate cancer. (NCI04);