" /> Gleason Score for Prostate Cancer - CISMeF





Preferred Label : Gleason Score for Prostate Cancer;

NCIt synonyms : Gleason Sum;

NCIt related terms : Gleason Score; gleason_score;

NCIt definition : The score derived from universally embraced prostate cancer grading system developed by Dr. Donald F. Gleason in 1977. The system provides a reproducible description of the glandular architecture of prostate tissue to which a pathologist assigns a score depending primarily on the microscopic patterns of cancerous glands and cell morphology. The system correlates well with behavior at the extremes: Gleason 1 1 tumors are the most well differentiated, slowly growing and rarely spread; Gleason 4 5 tumors are the most poorly differentiated, often widely metastatic at the time of diagnosis. In the commoner intermediate grade tumors, however, behavior is extremely variable.;

Alternative definition : NCI-GLOSS: A system of grading prostate cancer tissue based on how it looks under a microscope. Gleason scores range from 2 to 10 and indicate how likely it is that a tumor will spread. A low Gleason score means the cancer tissue is similar to normal prostate tissue and the tumor is less likely to spread; a high Gleason score means the cancer tissue is very different from normal and the tumor is more likely to spread.;

Codes from synonyms : CDR0000045696;

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16/05/2024


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