Pyroxamide - CISMeF

Preferred Label : Pyroxamide;

NCIt synonyms : Suberoyl-3-aminopyridineamide Hydroxamic Acid;

NCIt definition : A synthetic derivative of hydroxamic acid with antineoplastic properties, Pyroxamide inhibits histone deacetylases involved in transcription; induces hyperacetylation of core histones, modulating chromatin structure and affecting transcription of some genes that inhibit tumor growth; and induces growth arrest and apoptosis. Pyroxamide is used in clinical studies for cancer chemotherapy. (NCI04);

Alternative definition : NCI-GLOSS: A substance that is being studied as a treatment for cancer. It belongs to the family of drugs called histone deacetylase inhibitors.;

UNII : 12N86DSS23;

CAS number : 382180-17-8;

NSC code : 696085;

Codes from synonyms : NSC0696085; 31781; CDR0000269426;

Details

Origin ID

C2801;

UMLS CUI

C0966748;

Currated CISMeF NLP mapping
- pyroxamide [MeSH concept]
- pyroxamide [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- pyroxamide [MeSH Supplementary Concept]
- pyroxamide [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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