Preferred Label : PR18 (ras-13 Cys) Peptide;
NCIt synonyms : PR18 ras-13 Cys Peptide;
NCIt definition : A truncated synthetic form of the oncogene Ras, whose protein product p21 is located
in the plasma membrane and transduces growth and differentiation signals from activated
receptors to protein kinases within the cell. Because mutated Ras proteins may represent
highly specific epitopes for T-cell recognition, PR18 (ras-13 Cys) peptide may be
used in the vaccine immunotherapy of cancer. (NCI04);
Origin ID : C2792;
UMLS CUI : C1518808;
Semantic type(s)
- chemical_or_drug_has_mechanism_of_action
- chemical_or_drug_has_physiologic_effect
