TFE3-Rearranged Renal Cell Carcinoma

Preferred Label : TFE3-Rearranged Renal Cell Carcinoma;

NCIt synonyms : Xp11.2 Translocation-Related Renal Cell Carcinoma; Xp11 Translocation-Related Renal Cell Carcinoma; tRCC; Xp11 Translocation Renal Cell Carcinoma;

NCIt related terms : Renal Cell Cancer Associated with Xp11.2 Translocations/TFE3 Gene Fusions; Renal Cell Carcinoma Associated with Xp11.2 Translocations/TFE3 Gene Fusions;

NCIt definition : A group of renal cell carcinomas characterized by the presence of different translocations involving the chromosome Xp11.2. These translocations result in the creation of gene fusions involving the TFE3 gene. Patients are usually children and young adults. Morphologically, the malignant epithelial cells form papillary patterns.;

Neoplastic status : Malignant;

ICD-O code : 0000/0;

Détails

Origin ID

C27891;

UMLS CUI

C1337036;

Disease excludes abnormal cell
- Malignant Squamous Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Disease may have findings
- Flank Pain [NCIt concept]
- Hematuria [NCIt concept]
- Papillary Growth Pattern [NCIt concept]
- Psammoma Body Formation [NCIt concept]
Has associated anatomic sites
- Genitourinary System [NCIt concept]
- Kidney [NCIt concept]
- Kidney and Ureter [NCIt concept]
- Urinary System [NCIt concept]
Has cytogenetic abnormalities
- MiT Family Translocation [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
disease_has_abnormal_cell
- Adenocarcinoma Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Xp11.2 Translocations/TFE3 Gene Fusions Present [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Renal Tubular Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Renal Tubule Epithelium [NCIt concept]
disease_has_primary_anatomic_site
- Genitourinary System [NCIt concept]
- Kidney [NCIt concept]
- Renal Tubule [NCIt concept]
- Urinary System [NCIt concept]
disease_mapped_to_gene
- TFE3 Gene [NCIt concept]
pathogenesis_of_disease_involves_gene
- TFE3 Gene [NCIt concept]
- TFE3 wt Allele [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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