Castleman Disease, Hyaline-Vascular Type

Preferred Label : Castleman Disease, Hyaline-Vascular Type;

NCIt synonyms : Angiofollicular Lymphoid Hyperplasia, Hyaline-Vascular Type; Castleman's Disease, Hyaline-Vascular Type; Angiofollicular Lymphoid Hyperplasia Hyaline-Vascular Type;

NCIt definition : The commonest type of Castleman disease. It is seen most commonly in the mediastinum. Histologically this is characterized by hyalinized germinal centers surrounded by small lymphocytes in a concentric fashion, giving an onion skin appearance.;

Neoplastic status : Undetermined;

Details

Origin ID

C27853;

UMLS CUI

C1332293;

Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
Disease may have findings
- Interleukin-6 Overexpression [NCIt concept]
- Lymphadenopathy [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Sheets of Interfollicular Plasma Cells Present [NCIt concept]
disease_has_abnormal_cell
- Abnormal Hematopoietic and Lymphoid Cell [NCIt concept]
- Abnormal Lymphocyte [NCIt concept]
- Atypical Lymphocyte [NCIt concept]
disease_has_finding
- Germinal Centers with Prominent Hyalinized Vessels Present [NCIt concept]
- Lymphoplasmacytic Infiltrate [NCIt concept]
- Vascular Proliferation [NCIt concept]
disease_has_normal_cell_origin
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature Lymphocyte [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]

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