Nodular Sclerosis Classic Hodgkin Lymphoma, Syncytial Variant

Preferred Label : Nodular Sclerosis Classic Hodgkin Lymphoma, Syncytial Variant;

NCIt synonyms : Nodular Sclerosis Hodgkin Lymphoma, Syncytial Variant; Hodgkin's Disease, Nodular Sclerosis, Syncytial Variant; Hodgkin s Disease Nodular Sclerosis Syncytial Variant; Nodular Sclerosis Classical Hodgkin Lymphoma, Syncytial Variant;

NCIt related terms : Hodgkin disease, nodular sclerosis, syncytial variant;

NCIt definition : Nodular sclerosis classic Hodgkin lymphoma characterized by the presence of large numbers of Hodgkin and Reed-Sternberg cells forming confluent sheets.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL054962;

Details

Origin ID

C27807;

UMLS CUI

C5235045;

Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Plasma Cell [NCIt concept]
Disease may have findings
- CD15-Positive Neoplastic Cells Present [NCIt concept]
- CD30-Positive Neoplastic Cells Present [NCIt concept]
- Colony-Stimulating Factor Overexpression [NCIt concept]
- Fever [NCIt concept]
- Interleukin-10 Overexpression [NCIt concept]
- Interleukin-13 Overexpression [NCIt concept]
- Interleukin-2 Overexpression [NCIt concept]
- Interleukin-5 Overexpression [NCIt concept]
- Interleukin-6 Overexpression [NCIt concept]
- Interleukin-7 Overexpression [NCIt concept]
- Interleukin-9 Overexpression [NCIt concept]
- Lymphadenopathy [NCIt concept]
- Lymphotoxin-Alpha Overexpression [NCIt concept]
- Night Sweats [NCIt concept]
- Transforming Growth Factor-Beta Overexpression [NCIt concept]
- Weight Loss [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
See also inter- (CISMeF)
- Hodgkin disease, nodular sclerosis, syncytial variant [ICD-11 More detail]
- Hodgkin lymphoma, nodular sclerosis, grade 2 [ICD-11 More detail]
- Hodgkin lymphoma, nodular sclerosis, grade 2 (morphologic abnormality) [SNOMED CT concept]
- Hodgkin's disease, nodular sclerosis - lymphocytic depletion (disorder) [SNOMED CT concept]
- hodgkin's disease, nodular sclerosis, lymphocytic depletion [SNOMED Notion]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Hodgkin lymphoma, nodular sclerosis, grade 2 (morphologic abnormality) [SNOMED CT concept]
- Hodgkin's disease, nodular sclerosis - lymphocytic depletion (disorder) [SNOMED CT concept]
- hodgkin's disease, nodular sclerosis, lymphocytic depletion [SNOMED Notion]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Classic Reed-Sternberg Cell [NCIt concept]
- Hodgkin Cell [NCIt concept]
- Lacunar Reed-Sternberg Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
- Reed-Sternberg Cell [NCIt concept]
disease_has_finding
- Malignant Cellular Infiltrate [NCIt concept]
- Nodular Pattern [NCIt concept]
- Perivascular Fibrosis [NCIt concept]
- Syncytial Pattern [NCIt concept]
disease_has_normal_cell_origin
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature Lymphocyte [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_may_have_abnormal_cell
- Mummified Cell [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 12q [NCIt concept]
- Gain of Chromosome 2p [NCIt concept]
- Gain of Chromosome 9p [NCIt concept]
disease_may_have_molecular_abnormality
- Apoptotic Pathway Deregulation [NCIt concept]
- Clonal Immunoglobulin Heavy Chain Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Kappa Light Chain Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Lambda Light Chain Gene Rearrangement [NCIt concept]
- Clonal T-Cell Receptor Gene Rearrangement [NCIt concept]
disease_may_have_normal_cell_origin
- Mature B-Lymphocyte at the Germinal Center Stage of Differentiation [NCIt concept]
- Peripheral (Post-Thymic) T-Lymphocyte [NCIt concept]

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