Endometrial Atypical Hyperplasia/Endometrioid Intraepithelial Neoplasia

Preferred Label : Endometrial Atypical Hyperplasia/Endometrioid Intraepithelial Neoplasia;

NCIt synonyms : Endometrial Glandular Dysplasia; EmGD; EIN; Atypical Hyperplasia of the Endometrium; Endometrial Hyperplasia with Atypia; Endometrial Intraepithelial Neoplasia; EAH/EIN; Atypical Hyperplasia of Endometrium; Atypical Hyperplasia/Endometrioid Intraepithelial Neoplasm;

NCIt related terms : Endometrial intraepithelial neoplasia (EIN); Atypical Endometrial Hyperplasia; Atypical hyperplasia/Endometrial intraepithelial neoplasia (EIN);

NCIt definition : A neoplastic clonal expansion of endometrial glands characterized by cytologic changes of the epithelium and the presence of an increased number of endometrial glands. The glands form crowded aggregates with tubular or branching patterns which are cytologically distinct from the background architectural and cytological pattern. It is associated with molecular changes seen in endometrioid endometrial carcinoma, including microsatellite instability, PAX2 inactivation, and PTEN, KRAS, and CTNNB1 gene mutations.;

Neoplastic status : Undetermined;

Details

Origin ID

C27789;

UMLS CUI

C3812874;

Automatic exact mappings (from CISMeF team)
- Endometrial hyperplasia with atypia [ICD-9 code]
- Endometrial intraepithelial neoplasia [EIN] [ICD-9 code]
- Endometrioid intraepithelial neoplasia (morphologic abnormality) [SNOMED CT concept]
- endometrial hyperplasia [MeSH Descriptor]
Currated CISMeF NLP mapping
- Atypical endometrial hyperplasia (disorder) [SNOMED CT concept]
- Atypical hyperplasia of endometrium [MedDRA LLT]
- Endometrial intraepithelial neoplasia (disorder) [SNOMED CT concept]
- atypical endometrial hyperplasia [MeSH concept]
- atypical endometrium hyperplasia [Disease (Nov.)]
- endometrial intraepithelial neoplasia [Disease (Nov.)]
Disease excludes abnormal cell
- Dysplastic Squamous Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Disease may have findings
- Infertility [NCIt concept]
- Obesity [NCIt concept]
Has associated anatomic sites
- Corpus Uteri [NCIt concept]
- Endometrial Cavity [NCIt concept]
- Female Reproductive System [NCIt concept]
- Genitourinary System [NCIt concept]
- Reproductive System [NCIt concept]
- Uterus [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Endometrial intraepithelial neoplasia (disorder) [SNOMED CT concept]
- Endometrial intraepithelial neoplasia [EIN] [ICD-9 code]
- Endometrioid intraepithelial neoplasia [MedDRA LLT]
- Endometrioid intraepithelial neoplasia (morphologic abnormality) [SNOMED CT concept]
- endometrial intraepithelial neoplasia [Disease (Nov.)]
concept_is_in_subset
- CPTAC Baseline Medical Forms Terminology [NCIt concept]
- CPTAC Terminology [NCIt concept]
- CPTAC Uterine Corpus Endometrial Carcinoma Baseline Form [NCIt concept]
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
disease_excludes_finding
- Invasive Lesion [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
disease_has_abnormal_cell
- Dysplastic Glandular Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
disease_has_finding
- Dysplasia [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Hyperplastic Tissue Present [NCIt concept]
disease_has_normal_cell_origin
- Endometrial Glandular Cell [NCIt concept]
- Epithelial Cell [NCIt concept]
- Glandular Cell [NCIt concept]
disease_has_normal_tissue_origin
- Endometrium [NCIt concept]
- Epithelial Tissue [NCIt concept]
- Glandular Epithelium [NCIt concept]
disease_has_primary_anatomic_site
- Corpus Uteri [NCIt concept]
- Endometrial Cavity [NCIt concept]
- Female Reproductive System [NCIt concept]
disease_may_have_molecular_abnormality
- CTNNB1 Gene Mutation [NCIt concept]
- Inactivating PAX2 Gene Mutation [NCIt concept]
- KRAS Gene Mutation [NCIt concept]
- Microsatellite Instability [NCIt concept]
- PTEN Gene Mutation [NCIt concept]
may_be_associated_disease_of_disease
- Advanced Endometrial Endometrioid Adenocarcinoma [NCIt concept]
- Endometrial Endometrioid Adenocarcinoma [NCIt concept]
- Endometrial Endometrioid Adenocarcinoma with Clear Cell Change [NCIt concept]
- Endometrial Endometrioid Adenocarcinoma with Spindled Epithelial Cells [NCIt concept]
- Endometrial Endometrioid Adenocarcinoma with a Poorly Differentiated Carcinomatous Component [NCIt concept]
- Endometrial Endometrioid Adenocarcinoma with an Undifferentiated Carcinomatous Component [NCIt concept]
- Endometrial Endometrioid Adenocarcinoma, Ciliated Variant [NCIt concept]
- Endometrial Endometrioid Adenocarcinoma, Secretory Variant [NCIt concept]
- Endometrial Endometrioid Adenocarcinoma, Variant with Squamous Differentiation [NCIt concept]
- Endometrial High Grade Endometrioid Adenocarcinoma [NCIt concept]
- Endometrial Low Grade Endometrioid Adenocarcinoma [NCIt concept]
- FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma [NCIt concept]
- FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma [NCIt concept]
- Locally Advanced Endometrial Endometrioid Adenocarcinoma [NCIt concept]
- Metastatic Endometrial Endometrioid Adenocarcinoma [NCIt concept]
- Mismatch Repair-Deficient Endometrial Endometrioid Adenocarcinoma [NCIt concept]
- No Specific Molecular Profile Endometrial Endometrioid Adenocarcinoma [NCIt concept]
- Oxyphilic Endometrial Endometrioid Adenocarcinoma [NCIt concept]
- POLE-Ultramutated Endometrial Endometrioid Adenocarcinoma [NCIt concept]
- Recurrent Endometrial Endometrioid Adenocarcinoma [NCIt concept]
- Recurrent Endometrial High Grade Endometrioid Adenocarcinoma [NCIt concept]
- Recurrent Endometrial Low Grade Endometrioid Adenocarcinoma [NCIt concept]
- Refractory Endometrial Endometrioid Adenocarcinoma [NCIt concept]
- Villoglandular Endometrial Endometrioid Adenocarcinoma [NCIt concept]
- p53-Mutant Endometrial Endometrioid Adenocarcinoma [NCIt concept]

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