Alkylating Agent-Related Acute Myeloid Leukemia

Preferred Label : Alkylating Agent-Related Acute Myeloid Leukemia;

NCIt synonyms : Alkylating Agent Related Acute Myeloid Leukemia; Alkylating Agent-Related AML;

NCIt related terms : Therapy-related acute myeloid leukemia, alkylating agent related;

NCIt definition : Acute myeloid leukemia occurring as late complication of prior therapy with alkylating agents.;

Neoplastic status : Malignant;

Details

Origin ID

C27754;

UMLS CUI

C1321723;

Automatic exact mappings (from CISMeF team)
- Therapy-related acute myeloid leukemia and myelodysplastic syndrome (morphologic abnormality) [Inactive SNOMED CT concept]
Disease excludes abnormal cell
- Neoplastic Lymphoblast [NCIt concept]
Disease excludes normal cell origin
- Lymphocyte [NCIt concept]
Disease may have findings
- Auer Rods Present [NCIt concept]
- Bone Marrow Basophilia [NCIt concept]
- Bone Marrow Fibrosis [NCIt concept]
- Granulocytopenia [NCIt concept]
- Hypercellular Bone Marrow [NCIt concept]
- Pancytopenia [NCIt concept]
- Ring Sideroblasts 15 Percent or More of Erythroid Precursors [NCIt concept]
- Thrombocytopenia [NCIt concept]
- Unfavorable Clinical Outcome [NCIt concept]
Has associated anatomic sites
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Chronic Clinical Course [NCIt concept]
- Solid Growth Pattern [NCIt concept]
disease_has_abnormal_cell
- Hypolobated Neutrophil [NCIt concept]
- Leukemic Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Myeloblast [NCIt concept]
- Neoplastic Myeloid Blast [NCIt concept]
- Neoplastic Myeloid Cell [NCIt concept]
- Neutrophil with Cytoplasmic Hypogranularity [NCIt concept]
disease_has_finding
- Chemotherapeutic Agent Toxicity [NCIt concept]
- Drug Exposure [NCIt concept]
- Immature Myeloid Cells Increased in Bone Marrow [NCIt concept]
- Ineffective Hematopoiesis [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Myeloblasts 20 Percent or More of Bone Marrow Nucleated Cells [NCIt concept]
- Secondary Lesion [NCIt concept]
- Therapy-Related Toxicity [NCIt concept]
disease_has_normal_cell_origin
- Bone Marrow Stem Cell [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic Tissue [NCIt concept]
- Hematopoietic and Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
disease_mapped_to_chromosome
- Human Chromosome 5 [NCIt concept]
- Human Chromosome 7 [NCIt concept]
disease_may_have_abnormal_cell
- Dysplastic Megakaryocyte [NCIt concept]
disease_may_have_associated_disease
- Anemia [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Loss of Chromosome 5 [NCIt concept]
- Loss of Chromosome 7 [NCIt concept]

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