GM-CSF cDNA/Gold Complex

Preferred Label : GM-CSF cDNA/Gold Complex;

NCIt synonyms : GM-CSF cDNA/gold; GM-CSF cDNA-Gold Complex;

NCIt definition : Expression vectors containing the complementary DNA (cDNA) of the cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) coated onto gold particles. A protein cytokine secreted by T-cells and macrophages following cell activation by antigens or mitogens, GM-CSF is indispensable for the growth and development of granulocyte and macrophage progenitor cells. Subsequently, GM-CSF has been shown to activate and stimulate proliferation of mature macrophages and lymphocytes. (NCI04);

NSC code : 708478;

Details

Origin ID

C2756;

UMLS CUI

C1517366;

Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_cell_type_or_tissue
- Macrophage [NCIt concept]
- Monocyte [NCIt concept]
- T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Gene Regulation Process [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- Lymphocyte Activation Process [NCIt concept]
- Myeloid Cell Activation Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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