Atypical Spindle Cell/Pleomorphic Lipomatous Tumor

Preferred Label : Atypical Spindle Cell/Pleomorphic Lipomatous Tumor;

NCIt synonyms : Fibrosarcoma-Like Lipomatous Neoplasm; Spindle Cell Liposarcoma; Atypical Spindle Cell Lipoma;

NCIt definition : A benign adipocytic neoplasm, characterized by ill-defined tumor margins and the presence of variable proportions of mild to moderately atypical spindle cells, adipocytes, lipoblasts, pleomorphic cells, multinucleated giant cells, and a myxoid or collagenous extracellular matrix. It has a low tendency for local recurrence if incompletely excised. Unlike conventional atypical lipomatous tumors, there is no risk for dedifferentiation. (WHO 2020);

Neoplastic status : Benign;

Details

Origin ID

C27489;

UMLS CUI

C1275275;

Currated CISMeF NLP mapping
- Spindle cell liposarcoma (disorder) [SNOMED CT concept]
- spindle cell liposarcoma [DO Concept]
DO Cross reference
- spindle cell liposarcoma [DO Concept]
Disease excludes abnormal cell
- Malignant Cell [NCIt concept]
Disease excludes normal cell origin
- Neuron, Neuroepithelial Cell, and Supporting Cell of the Nervous System [NCIt concept]
Disease may have findings
- Fibrotic Stroma Formation [NCIt concept]
- Myxoid Stroma Formation [NCIt concept]
Has associated anatomic sites
- Connective and Soft Tissue [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Spindle cell liposarcoma (disorder) [SNOMED CT concept]
- spindle cell liposarcoma [DO Concept]
disease_excludes_finding
- Locally Aggressive Lesion [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Neoplastic Cell [NCIt concept]
- Neoplastic Connective and Soft Tissue Cell [NCIt concept]
- Neoplastic Lipoblast [NCIt concept]
- Neoplastic Lipocyte [NCIt concept]
- Neoplastic Multinucleated Giant Cell [NCIt concept]
- Neoplastic Spindle Cell [NCIt concept]
- Pleomorphic Cell [NCIt concept]
disease_has_finding
- Atypia [NCIt concept]
- Benign Cellular Infiltrate [NCIt concept]
- Indolent Clinical Course [NCIt concept]
disease_has_normal_cell_origin
- Adipocyte [NCIt concept]
- Connective and Soft Tissue Cell [NCIt concept]
disease_has_normal_tissue_origin
- Adipose Tissue [NCIt concept]
- Connective and Soft Tissue [NCIt concept]

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