Nimotuzumab - CISMeF

Preferred Label : Nimotuzumab;

NCIt synonyms : TheraCim hR3; Thera-CIM-hr3;

NCIt related terms : Theraloc;

NCIt definition : A humanized monoclonal antibody directed against the epidermal growth factor receptor (EGFR) with potential antineoplastic activity. Nimotuzumab binds to and inhibits EGFR, resulting in growth inhibition of tumor cells that overexpress EGFR. This agent may act synergistically with radiation therapy.;

Alternative definition : NCI-GLOSS: A monoclonal antibody being studied in the treatment of some types of cancer. Monoclonal antibodies are made in the laboratory and can locate and bind to substances in the body, including cancer cells. Nimotuzumab binds the epidermal growth factor receptor (EGFR) and blocks cancer cells that depend on epidermal growth factor for growth.;

UNII : 6NS400BXKH;

CAS number : 828933-51-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 828933-51-3 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Theraloc;

Molecule name : H-R3;

Codes from synonyms : CDR0000538634; CDR0000572210;

Details

Origin ID

C2733;

UMLS CUI

C1570308;

Automatic exact mappings (from CISMeF team)
- TheraCIM [MeSH concept]
- theracim-HR3 [MeSH concept]
See also inter- (CISMeF)
- TheraCIM [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Nimotuzumab (substance) [SNOMED CT concept]
- nimotuzumab [MeSH Supplementary Concept]
- nimotuzumab [MeSH concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Epidermal Growth Factor Receptor [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients