NCIt definition : Point-mutation products of Ras proto-oncogene are found to associated with a broad
spectrum of human carcinomas. Mutation locations are notably at codons 12, 13, and
61. Codon 12 mutations form more than 90% of all Ras mutations in human cancers. Degraded
Ras peptides have been shown to stimulate immunogenic response. Various forms of mutated
Ras peptides-adjuvant are used as vaccine along with cytokines that could potentially
enhance the body's immunological response in many neoplastic conditions. (NCI04);