" /> Therapeutic Immune Globulin - CISMeF





Preferred Label : Therapeutic Immune Globulin;

NCIt synonyms : Immune Globulin Intravenous; Therapeutic Immunoglobulin; IgIV; Immune Globulin IV;

NCIt related terms : Immune Globulin; Gamma Globulin;

NCIt definition : A preparation of plasma proteins derived from the pooled plasma of adult donors. Largely comprised of IgG antibodies, therapeutic immune globulin provides passive immunization by increasing the recipient's serum levels of circulating antibodies. IgG antibodies have multiple functions, including binding to and neutralizing bacterial toxins; opsonization of pathogens; activation of complement; and suppression of pathogenic cytokines and phagocytes through binding to CD5, interleukin-1a (IL-1a), interleukin 6 (IL-6), tumor necrosis factor-alpha (TNF-alpha), and T-cell receptors. Therapeutic immune globulin may diminish pathogenic mechanisms in some autoimmune diseases by binding to and inhibiting the activity of autoantibodies. (NCI04);

Alternative definition : NICHD: A blood product derived from pooled IgG antibodies extracted from donor plasma delivered parenterally. It is used to treat multiple disorders, including immunodeficiencies, autoimmune disorders, and active infections.;

Drug name : Sandoglobulin; Panglobulin; Iveegam EN; Gammar-P; Gamimune N; Polygam S/D; Gammagard S/D; BayGam; Venoglobulin-I; WinRho SDF; Venoglobulin-S; Panzyga;

NSC code : 621996;

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21/05/2024


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