Selective IgA Immunodeficiency

Preferred Label : Selective IgA Immunodeficiency;

NCIt definition : A dysgammaglobulinemia characterized by low or undetectable serum levels of immunoglobulin class A (IgA). It is the most common primary antibody deficiency. It may be inherited or the reversible sequela of infection or certain drugs. It may be caused by decreased or inefficient class-switching from progenitor B cells without any corresponding decreases in the other isotypes. Though affected persons may be asymptomatic, low levels of IgA will reduce the immune system's ability to combat infection where IgA is normally secreted, at mucosal surfaces. Selective IgA deficiency is seen in greater proportion among patients with autoimmune disorders.;

Details

Origin ID

C26964;

UMLS CUI

C4049006;

Automatic exact mappings (from CISMeF team)
- Selective IgA immunodeficiency [ICD-9 code]
- Selective deficiency of immunoglobulin A [ICD-11 More detail]
- selective IgA deficiency disease [DO Concept]
Currated CISMeF NLP mapping
- IgA deficiency [MedDRA LLT]
- Immunoglobulin a deficiency 1 [OMIM Phenotype]
- Secretory IgA deficiency [HPO term]
- Selective IgA immunodeficiency [MedDRA Preferred Term]
- Selective deficiency of immunoglobulin A [IgA] [ICD-10 Sub-category (who)]
- Selective deficiency of immunoglobulin A [IgA] [ICD-10 Sub-category]
- Selective immunoglobulin A deficiency (disorder) [SNOMED CT concept]
- immunoglobulin a deficiency 1 [MeSH Supplementary Concept]
- selective immunoglobulin A deficiency [Disease (Nov.)]
Semantic type(s)
- Disease or Syndrome [UMLS semantic type]
UMLS correspondences (same concept)
- Selective IgA immunodeficiency [MedDRA Preferred Term]
- Selective IgA immunodeficiency [ICD-9 code]
- Selective deficiency of immunoglobulin A [IgA] [ICD-10 Sub-category]
- Selective immunoglobulin A deficiency (disorder) [SNOMED CT concept]

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