NCIt definition : A Cremophor EL-free, albumin-stabilized nanoparticle formulation of the natural taxane
paclitaxel with antineoplastic activity. Paclitaxel binds to and stabilizes microtubules,
preventing their depolymerization and so inhibiting cellular motility, mitosis, and
replication. This formulation solubilizes paclitaxel without the use of the solvent
Cremophor, thereby permitting the administration of larger doses of paclitaxel while
avoiding the toxic effects associated with Cremophor.;
Alternative definition : NCI-GLOSS: A drug used to treat breast cancer that has spread or that has come back
within 6 months after chemotherapy. It is also being studied in the treatment of newly
diagnosed breast cancer and other types of cancer. ABI-007 is a type of mitotic inhibitor.;
Drug name : Abraxane; Naveruclif;
Molecule name : ABI 007; ABI-007;
NSC code : 736631;
Codes from synonyms : CDR0000488416; CDR0000507751; CDR0000367434; CDR0000507600; CDR0000507601; 378;