" /> Nab-paclitaxel - CISMeF





Preferred Label : Nab-paclitaxel;

NCIt synonyms : Albumin-Stabilized Nanoparticle Paclitaxel; Albumin-bound Paclitaxel; Nanoparticle Albumin-bound Paclitaxel; Paclitaxel Albumin; Paclitaxel Protein-Bound;

NCIt related terms : Abraxane; ABI-007; nanoparticle paclitaxel; paclitaxel albumin-stabilized nanoparticle formulation; protein-bound paclitaxel; Paclitaxel nanoparticle albumin-bound;

NCIt definition : A Cremophor EL-free, albumin-stabilized nanoparticle formulation of the natural taxane paclitaxel with antineoplastic activity. Paclitaxel binds to and stabilizes microtubules, preventing their depolymerization and so inhibiting cellular motility, mitosis, and replication. This formulation solubilizes paclitaxel without the use of the solvent Cremophor, thereby permitting the administration of larger doses of paclitaxel while avoiding the toxic effects associated with Cremophor.;

Alternative definition : NCI-GLOSS: A drug used to treat breast cancer that has spread or that has come back within 6 months after chemotherapy. It is also being studied in the treatment of newly diagnosed breast cancer and other types of cancer. ABI-007 is a type of mitotic inhibitor.;

Drug name : Abraxane;

Molecule name : ABI 007; ABI-007;

NSC code : 736631;

Codes from synonyms : CDR0000488416; CDR0000507751; CDR0000367434; CDR0000507600; CDR0000507601; 378;

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15/05/2024


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