Preferred Label : Monoclonal Antibody D6.12;
NCIt synonyms : MoAb D612; MoAb D6.12; Monoclonal Antibody D6 12;
NCIt definition : A murine IgG2a monoclonal antibody directed against a 48 kDa antigen expressed on
the cell surface of normal and malignant gastrointestinal epithelium. MoAb D6.12 has
been shown to induce antibody-dependent cell-mediated cytotoxicity (ADCC). This MoAb,
either alone or in combination with other immunotherapeutic agents, may have possible
diagnostic or therapeutic applications in gastrointestinal cancers.;
PubMed : 8402627;
Origin ID : C2683;
UMLS CUI : C1134661;
Semantic type(s)
- chemical_or_drug_has_mechanism_of_action
- concept_is_in_subset
