Sinusoidal Obstruction Syndrome

Preferred Label : Sinusoidal Obstruction Syndrome;

NCIt synonyms : Liver Veno-Occlusive Disease;

NCIt related terms : hepatic veno-occlusive disease;

NCIt definition : A disorder characterized by inflammation and damage of the hepatic sinusoidal endothelial cells of the hepatic venules that leads to venular occlusion and hepatocellular necrosis. It is most often a conditioning-related toxicity that results as a complication of hematopoietic stem cell transplantation (HSCT). It has also been described in populations of individuals who have ingested pyrrolizidine plant alkaloids. The clinical signs and symptoms include hyperbilirubinemia, hepatomegaly, and fluid retention.;

Alternative definition : NCI-GLOSS: A condition in which some of the veins in the liver are blocked. It is sometimes a complication of high-dose chemotherapy given before a bone marrow transplant and is marked by increases in weight, liver size, and blood levels of bilirubin.;

Codes from synonyms : CDR0000044806; K76.5;

Details

Origin ID

C26793;

UMLS CUI

C0019156;

Currated CISMeF NLP mapping
- Hepatic veno-occlusive disease [ICD-10 Sub-category]
- Hepatic veno-occlusive disease [ICD-11 Subcategory]
- Hepatic veno-occlusive disease [ICD-10 Sub-category (who)]
- Hepatic veno-occlusive disease [ORDO Disease]
- Sinusoidal obstruction syndrome [MedDRA LLT]
- VENOOCCLUSIVE LIVER DISEASE [WHO-ART Preferred Term]
- Veno-occlusive disease of the liver (disorder) [SNOMED CT concept]
- Venoocclusive liver disease [MedDRA Preferred Term]
- hepatic Veno-Occlusive disease [MeSH concept]
- hepatic veno-occlusive disease [DO Concept]
- hepatic veno-occlusive disease [MeSH Descriptor]
- liver venoocclusive disease [Disease (Nov.)]
- veno-occlusive disease of the liver [SNOMED Notion]
Has associated anatomic sites
- Cardiovascular System [NCIt concept]
- Digestive System [NCIt concept]
- Hepatobiliary System [NCIt concept]
- Liver [NCIt concept]
- Vascular System [NCIt concept]
Semantic type(s)
- Disease or Syndrome [UMLS semantic type]
UMLS correspondences (same concept)
- Hepatic sinusoidal obstruction syndrome [MedDRA LLT]
- Hepatic veno-occlusive disease [ORDO Disease]
- Hepatic veno-occlusive disease [ICD-10 Sub-category]
- Hepatic veno-occlusive disease [ICD-11 Subcategory]
- Hepatic veno-occlusive disease [ICD-10 Sub-category (who)]
- Sinusoidal obstruction syndrome [MedDRA LLT]
- VENOOCCLUSIVE LIVER DISEASE [WHO-ART Preferred Term]
- Veno-occlusive disease of the liver (disorder) [SNOMED CT concept]
- Venoocclusive liver disease [MedDRA Preferred Term]
- Venoocclusive syndrome of the liver [MedDRA LLT]
- hepatic Veno-Occlusive disease [MeSH concept]
- hepatic veno-occlusive disease [DO Concept]
- hepatic veno-occlusive disease [MeSH Descriptor]
- liver venoocclusive disease [Disease (Nov.)]
- veno-occlusive disease of the liver [SNOMED Notion]
concept_is_in_subset
- ALL Authorized Value Terminology [NCIt concept]
- ALL Survival Characteristics Table [NCIt concept]
- AML Adverse Events Table [NCIt concept]
- AML Authorized Value Terminology [NCIt concept]
- AML Survival Characteristics Table [NCIt concept]
- mCode Elixhauser Moderate to Severe Liver Disease Value Set [NCIt concept]
- mCode Terminology [NCIt concept]
disease_has_primary_anatomic_site
- Blood Vessel [NCIt concept]
- Liver [NCIt concept]

Keyword's position in hierarchy(ies) :

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