" /> Endothelin Receptor Type A Antagonist YM598 - CISMeF





Preferred Label : Endothelin Receptor Type A Antagonist YM598;

NCIt synonyms : Potassium (E)-N-[6-methoxy-5-(2-methoxyphenoxy)-2-(pyrimidin-2-yl)pyrimidin-4-yl]-2-phenylenthene Sulfonamidate;

NCIt related terms : NEBENTAN POTASSIUM; YM598;

NCIt definition : An orally active synthetic substituted phenylethenesulfonamide. As a selective endothelin A receptor antagonist, YM598 inhibits endothelin-mediated mechanisms involved in tumor cell growth and progression, angiogenesis, and metastasis. (NCI04);

Alternative definition : NCI-GLOSS: A substance that is being studied as a treatment for advanced prostate cancer and for pain caused by prostate cancer that has spread to the bone. It belongs to the family of drugs called endothelin ETA receptor antagonists.;

UNII : OK6K3MDZ98;

CAS number : 342005-82-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 342005-82-7 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : YM598;

Codes from synonyms : CDR0000302471;

PubMed : 16843458;

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09/05/2024


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