Talaporfin Sodium

Preferred Label : Talaporfin Sodium;

NCIt synonyms : Taporfin Sodium; Mono-L-aspartyl Chlorin e6; NPe6;

NCIt definition : An agent consisting of chlorin e6, derived from chlorophyll, and L-aspartic acid with photosensitizing activity. After intratumoral activation by light emitting diodes, taporfin sodium forms an extended high energy conformational state that generates singlet oxygen, resulting in free radical-mediated cell death. (NCI04);

Alternative definition : NCI-GLOSS: A drug used in photodynamic therapy. When absorbed by cancer cells and exposed to light, the drug becomes active and kills the cancer cells.;

UNII : L63605PZ70;

InChIKey : KPALSRNVSRWOPA-YJFNSWLASA-J;

CAS number : 220201-34-3;

Drug name : Laserphyrin;

Molecule name : LS11; ME2906;

Chemical formula : C38H37N5O9.4Na;

Codes from synonyms : CDR0000305997;

Details

Origin ID

C26675;

UMLS CUI

C1312955;

Automatic exact mappings (from CISMeF team)
- Talaporfin [MeSH concept]
- Talaporfin [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- talaporfin sodium [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- talaporfin sodium [MeSH concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_free_acid_or_base_form
- Talaporfin [NCIt concept]
is_salt_form_of
- Talaporfin [NCIt concept]

Keyword's position in hierarchy(ies) :

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