NCIt definition : A synthetic central nervous system stimulant with wakefulness-promoting activity.
Modafinil appears to inhibit dopamine reuptake, resulting in an increase in extracellular
dopamine. This agent exhibits pronounced wakefulness-promoting activity (without sympathomimetic
activity) and may improve cognitive function in certain clinical settings. (NCI04);
Alternative definition : NCI-GLOSS: A drug that is being studied as a treatment for fatigue in patients with
cancer. It belongs to the family of drugs called stimulants.;