ZAP70 Gene - CISMeF

Preferred Label : ZAP70 Gene;

NCIt synonyms : Zeta-Chain (TCR) Associated Protein Kinase 70kDa Gene; ZAP-70 Gene;

NCIt related terms : ZAP70;

CISMeF acronym : ZAP70;

NCIt definition : This gene is involved in tyrosine phosphorylation and T-cell activation.;

Details

Origin ID

C26535;

UMLS CUI

C1421567;

Automatic exact mappings (from CISMeF team)
- ZAP70 [LOINC component]
- ZAP70 cells [LOINC component]
- Zeta-chain-associated protein kinase [OMIM gene]
- zeta chain of T-cell receptor associated protein kinase 70 [ORDO Gene]
HGNC gene
- zeta chain of T cell receptor associated protein kinase 70 [HGNC gene]
OMIM relation
- Zeta-chain-associated protein kinase [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- Zeta-chain-associated protein kinase [OMIM gene]
- zeta chain of T cell receptor associated protein kinase 70 [HGNC gene]
gene_associated_with_disease
- Severe Combined Immunodeficiency [NCIt concept]
gene_encodes_gene_product
- Tyrosine-Protein Kinase ZAP-70 [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_abnormality
- ZAP70 Messenger RNA Overexpression [NCIt concept]
gene_involved_in_molecular_abnormality
- ZAP70 Messenger RNA Overexpression [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Chronic Lymphocytic Leukemia with Unmutated Immunoglobulin Heavy Chain Variable-Region Gene [NCIt concept]
- Small Lymphocytic Lymphoma with Unmutated Immunoglobulin Heavy Chain Variable-Region Gene [NCIt concept]
gene_mapped_to_disease
- Chronic Lymphocytic Leukemia with Unmutated Immunoglobulin Heavy Chain Variable-Region Gene [NCIt concept]
- Immunodeficiency 48 [NCIt concept]
- Small Lymphocytic Lymphoma with Unmutated Immunoglobulin Heavy Chain Variable-Region Gene [NCIt concept]
gene_plays_role_in_process
- Cell Differentiation Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Proliferation [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Signal Transduction [NCIt concept]
- T-Cell Activation [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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