Preferred Label : Synchrotope TA2M Plasmid DNA Vaccine;
NCIt definition : A recombinant plasmid DNA vaccine encoding epitopes of tyrosinase with potential antineoplastic
activity. Synchrotope TA2M vaccine contains a plasmid encoding 2 epitopes, amino acid
sequences 207-216 and 1-17 of tyrosinase, a protein frequently expressed by melanoma
cells. Vaccination with the TA2M plasmid DNA vaccine may induce the production of
anti-tyrosinase antibodies as well as elicit a cytotoxic T-lymphocyte (CTL) response
against tyrosinase-expressing tumor cells, resulting in decreased tumor growth.;
Origin ID : C2650;
UMLS CUI : C1134471;
Semantic type(s)
- concept_is_in_subset
