Preferred Label : Dendritic Cell-Autologous Lung Tumor Vaccine;
NCIt synonyms : DCVax-Lung; DCVax-L;
NCIt definition : A cancer vaccine consisting of lymphocytes harvested from a patient with lung cancer
and induced to become antigen-presenting cells (APCs) known as dendritic cells. The
dendritic cells are transduced with the gene encoding an antigen specific to the patient's
cancer and then returned to the patient. In the host, the altered cells stimulate
the immune system to mount a primary T cell response against lung tumor cells expressing
the target antigen. Dendritic cell-autologous lung tumor vaccines have been investigated
for use in cancer immunotherapy. (NCI04);
Origin ID : C26446;
UMLS CUI : C1327750;
Semantic type(s)
- concept_is_in_subset
