Preferred Label : I 131 Monoclonal Antibody CC49;
NCIt synonyms : Iodine I 131 Monoclonal Antibody CC49;
NCIt definition : A radioimmunoconjugate of the humanized monoclonal antibody CC49 labeled with iodine
I 131. Iodine I 131 monoclonal antibody CC49 delivers beta and gamma radiation-emitting
I 131 radionuclide specifically to tumor cells that express tumor-associated glycoprotein
(TAG)-72, allowing localization of TAG-72-expressing tumor cells with radioimaging
devices in diagnostic applications or resulting in specific TAG-72-expressing tumor
cell radiocytotoxicity in therapeutic applications. Monoclonal antibody CC49 binds
to TAG-72, a pancarcinoma antigen, with high affinity.;
Origin ID : C26442;
UMLS CUI : C1327845;
Semantic type(s)
- concept_is_in_subset
