Midkine - CISMeF

Preferred Label : Midkine;

NCIt synonyms : MDK; Amphiregulin-Associated Protein; Midgestation and Kidney Protein; Neurite Outgrowth-Promoting Protein; Neurite Outgrowth-Promoting Factor 2; Neurite Growth-Promoting Factor-2; ARAP; Retinoic Acid Inducible Factor; MK; Neurite Growth-Promoting Factor 2;

NCIt definition : Midkine (143 aa, 16 kDa) is encoded by the human MDK gene. This protein plays a role in receptor signaling and the modulation of cell proliferation.;

NCIt note : Midkine exhibits neurite outgrowth-promoting activity and may play a role in nervous system development and/or maintenance. (OMIM);

Details

Origin ID

C26381;

UMLS CUI

C0083453;

Currated CISMeF NLP mapping
- Midkine [MeSH Descriptor]
- midkine [MeSH concept]
False automatic mappings
- Meckel syndrome, type 1 [OMIM Phenotype]
OMIM relation
- Midkine [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- MDK protein, human [MeSH Supplementary Concept]
- MDK protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Growth Factor Gene [NCIt concept]
- MDK Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Heparin Binding Growth Factor [NCIt concept]
- Ligand Binding Protein [NCIt concept]
gene_product_is_element_in_pathway
- Glypican 2 Signaling Pathway [NCIt concept]
- Syndecan-4-Mediated Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Heparin Binding [NCIt concept]
- Neural Development [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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